backbones filtering
In design binders via RFdiffusion and ProteinMPNN-FastRelax, at the beginning of sequence design and binder assessment script mpnn_af.slm
, we could perform a fitering step to remove useless backnones.
In my opinion, this is a very heloful step, because it greatly increase the speed and efficiency of desigining reasonable binders. For example, in my target.pdb
, I only expect designed binders could bind with the outside part of the target.pdb
(see fig.1).

